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Master Scientist - Toxicologist

Date: Mar 14, 2019

Location: Winston Salem, NC, US

Company: RAI

Reynolds American Incorporated is positively transforming the tobacco industry. We’re a family of companies that strives for success in everything we do. The future inspires us because our people are igniting the breakthroughs that are redefining the ways adult tobacco consumers enjoy tobacco in the 21st century.

When other companies talk about growth, they only talk about size. At RAI, we focus on the growth of our people. We take pride in each other’s growth and well-being throughout our careers. We invest in your career and total well-being because we know our companies succeed when our people thrive.

At the RAI companies you’ll have the opportunity to work on iconic brands and revolutionary products by collaborating with visionary, principled and passionate people every day.

This position is within Reynolds American Services Company—a subsidiary that provides support services, including compliance, HR, law, finance, information management, and more to all of the subsidiaries of RAI.

 

RAIS Services Company (RAIS) is seeking a qualified, well-organized Master Scientist with in vitro toxicology expertise to support the assessment of enterprise-wide tobacco products consistent with Growth, Innovation and Harm Reduction platforms. The Nonclinical Toxicologist (Master Scientist) will be involved in developing and applying in vitro toxicology assays and methods for acceptance by regulatory agencies, as well as exploring new experimental approaches for characterizing issues related to mutagenesis, carcinogenesis and related effects.

 

The incumbent will design and manage studies, review data and report results from standardized/established in vitro toxicology assays conducted at Contract Research Organizations (CROs).  They will have the responsibility of acting as an internal and external in vitro toxicology Subject Matter Expert who will support ongoing activities required for regulatory submissions.  Additionally, the individual will propose and validate new assays/supporting technologies through confident, interactive engagement with internal stakeholders, other internal and external in vitro toxicology experts, including relevant CROs, with the objective of driving growth/development in the in vitro regulatory toxicology field. 

 

Principal Duties and Responsibilities:

 

  • Serve as internal and external Subject Matter Expert regarding in vitro toxicology assays, specifically for regulatory submissions.
  • Engage with stakeholders to determine company needs, develop scientific strategy and implement ideas that contribute to the company’s vision.
  • Lead external engagement initiatives and provide forward-thinking scientific thought leadership with external groups, companies or organizations. 
  • Review, interpret and/or apply research concepts from the scientific literature to RAIS nonclinical studies.
  • Work with CROs and other external partners to develop, validate and/or qualify in vitro assays/related technology to support product assessment as well as regulatory submissions and engagement.
  • Lead, contribute to, and/or assist with design and interpretation of nonclinical studies.
  • Lead, contribute to, and/or assist with the preparation and publication of scientific results obtained from RAIS’s nonclinical studies in peer-reviewed scientific journals and present, as appropriate, at scientific meetings.
  • Manage or oversee the logistics of project initiation and implementation at CROs, for multiple studies simultaneously, and under heightened time constraints.
  • Direct the selection and qualification of applicable CROs.
  • Conduct onsite monitoring visits and technical/compliance audits, and observe critical study phase procedures.
  • Mentor and guide the development of other in vitro toxicologists within the group.
  • Ensure GLP compliance in all applicable studies.
  • Self-motivated and works with a sense of urgency; orientation to creativity, innovation, and action

 

POSITION QUALIFICATIONS

 

Required Knowledge and Experience:

 

  • PhD required in Toxicology, Pharmacology, Biochemistry or closely related discipline; minimum of 5 years’ relevant experience conducting in vitro toxicology studies in industry (e.g. tobacco, pharma), academia or regulatory science.
  • Ability to travel internationally.
  • Experience in publication and presentation of scientific data.
  • Strong theoretical/experimental background in mammalian toxicology
  • Ability to successfully navigate a dynamic work environment with evolving priorities

 

Preferred:

  • Experience with FDA regulatory submissions, including 4 or more years’ experience in the conduct of nonclinical studies compliant with 21 CFR part 58 and part 11 and/or OECD GLP regulatory requirements.

 

Ideal Candidate:

  • Demonstrated ability to engage, influence, and collaborate with internal and external resources in order to meet regulatory and business objectives.
  • Demonstrated project management and teamwork skills.
  • Established publication record in peer-reviewed journals; including primary authorship.
  • Diplomate of the American Board of Toxicology (DABT) is advantageous.
  • Broad understanding of the tobacco category, nonclinical tobacco research and relevant industry experience.
  • Experience with complex cell models.
  • Experience with molecular biology assays.
  • Knowledge of mechanisms of smoking-related diseases.
  • Experience in international working group(s) focused on methods standardization.


Compensation/Targeted Bonus

  • Competitive Annual Salary
  • Targeted Annual Bonus
  • Relocation assistance available for those who qualify.

 

Benefit Summary

Our company offers very competitive compensation and benefit plans, including:

  • 401(k) plan that offers opportunity to save on pre- and post-tax basis up to 50 percent of eligible compensation. Company matches 100 percent of employee pre-tax/Roth (401k) contributions up to six percent
  • Comprehensive health- and welfare-benefits package
  • Eleven paid company holidays annually, plus a generous paid vacation plan based on length of service
  • Company-paid sick and personal days, funeral leave and jury duty leave
  • Confidential personal financial counseling service
  • On-site health clinics and fitness centers
  • A matching grants program that enables employees to direct and double their donations to qualifying charitable organizations of their choice
  • Health-care advocacy service
  • Volunteer service opportunities
  • Federal credit union membership through Allegacy Federal Credit Union
  • Extensive training opportunities  

 

ABOUT OUR ORGANIZATION:

Reynolds American Inc. is an indirect, wholly owned subsidiary of British American Tobacco p.l.c., and the U.S. parent company of R. J. Reynolds Tobacco Company; Santa Fe Natural Tobacco Company, Inc.; American Snuff Company, LLC; Niconovum USA, Inc.; Niconovum AB; R. J. Reynolds Vapor Company; Lorillard Licensing Company, LLC; and Reynolds Brands, Inc..


Reynolds American Inc. and its affiliated companies is an Equal Opportunity / Affirmative Action Employer.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Our organization offers a level of challenge, responsibility and creativity for motivated employees that stands apart from the crowd.

We are also committed to employing a diverse workforce and valuing different perspectives, experiences and talents to maximize the company's potential for successfully achieving its business objectives.

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Only applicants requiring reasonable accommodation for any part of the application and hiring process should contact us directly.

Email: TalentAcquisition@RJRT.com


Nearest Major Market: Winston-Salem

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